The Minnesota Football Coaches Association (MFCA) and the Minnesota Vikings have announced the 12 coaches and 88 players who will participate in the 2022 Minnesota High School Football All-Star Game (49th Annual MFCA All-Star Football Game). The 49th Annual All-Star Game will showcase outstanding senior players from the 2022 Minnesota high school football season.

The Minnesota High School Football All-Star Game is sponsored by the Minnesota Vikings and the Minnesota Football Coaches Association (MFCA) and is presented by Andersen.